Find Nalmefene HCL Cas 58895-64-0, Nalmefene Hydrochloride CAS Number 58895-64-0, 58895-64-0 on Industry Directory, Reliable Manufacturer/Supplier/Factory from China.

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Universal Opioid Receptor Antagonist Nalmefene Hydrochloride CAS 58895-64-0

Universal Opioid Receptor Antagonist Nalmefene Hydrochloride CAS 58895-64-0

    Payment Type: T/T
    Terms of Trade: CIF
    Min. Order: 1 Kilogram
    Delivery Time: 15 Days
    Packaging: AS REQUIRED
    Productivity: KGS
    Brand: VOLSENCHEM
    Transportation: Air
    Place of Origin: CHINA
    Supply Ability: TRUE MANUFACTURER
    Certificate: ISO

Basic Info

Model No.: 58895-64-0

Product Description

Nalmefene hydrochloride cas number 58895-64-0,As a highly selective and specific endogenous opioid receptor antagonist, does not have the agonistic effect of opioids, but competes with the endogenous excess of endogenous opioid peptides. The method can bind to endogenous opioid receptors μ, κ, and δ, and the binding to mu receptor is the strongest. Nalmefene hydrochloride cas 58895-64-0 blocks a series of pathological reactions caused by central nervous system, respiratory and circulatory system caused by stress, and can inhibit or reverse the respiratory depression, sedation and hypotension of opioids; Or the treatment of synthetic anesthetic analgesic poisoning, also has some antagonism against some non-opioid poisoning, such as reversing the respiratory depression and coma caused by alcohol overdose.In 1995, nalmefene hydrochloride was listed in the United States. It is another new pure opioid receptor antagonist synthesized after naloxone and naltrexone. It is a derivative of water-soluble naltrexone, and its chemical structure of the 6-methylene group makes it exhibit physiologically stronger and more penetrating biofilm properties. Its plasma elimination half-life is 8.2-8.9h, compared with the similar compounds naloxone and naltrexone, its pharmacological action is long and the intensity of action is large. Poor side effects. Although there are slight headaches, burnout, blurred vision, etc. at higher doses, there is no obvious adverse reaction, so it is getting more and more attention from researchers. In 1995, approved by the US FDA, nalmefene hydrochloride was used to reverse the adverse reactions caused by opioids such as respiratory depression and blood pressure after surgery.
Currently, clinically, a formulation containing nalmefene hydrochloride is an oral preparation for oral administration and an injection for intravenous and intramuscular administration. Experiments show that nalmefene hydrochloride has the characteristics of long acting time, high bioavailability and few side effects. It has been used to antagonize respiratory depression caused by narcotic analgesics and for heart failure, shock, alcoholism, addiction, etc. treatment.

Thera. Category:Receptor antagonist

Cas No.: 58895-64-0

58895-64-0

Synonym:Revex;Unii-K7K69qc05x;(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diolhydrochloride;(5a)-17-(CyclopropylMethyl)-6-Methylene-4,5-epoxyMorphinan-3,14-diol;17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride;nalmefene hydrochloride;NALMEFENE HCL;Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, hydrochloride, (5alpha)-;

Molecular Formula:C21H25NO3.ClH

Molecular Weight:375.89

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request


Taizhou Volsen Chemical Co., Ltd.

 

Taizhou Volsen Chemical Co., Ltd. is professional in R&D, producing and marketing Pharmaceutical raw materials, pharmaceutical intermediates in China. VOLSEN consists of about 100 experienced employees including 3 PhD and 10 Master, and 35000 sqm facilities including research laboratories, kilo lab, pilot plant and full manufacturing plant,


VOLSEN R&D specialists, quality manager and sales with abundance experience make sure products are reliable and service is professional. The producing person inspect every step of the whole process and check up the quality strictly, in order to insure every batch of raw material achieve the standard of EP,CP, JP,BP etc.Matching to the diversified requirements of companies VOLSEN is steadily marching to reach the peaks.


Volsen owns a professional custom synthesis department, with more than 15 senior scientific research chemical personnels who have a graduate degree or above. We also have an independent scientific management system. Our company integrates years of production experiences and talent reserves that forms a strong R&D production capacity, furthermore we could undertake various chemicals customizations from kg to ton relying on the existing production base and equipment.


Manufacturing Unit is equipped with a facility of progressive reeducation of emissions, effluents and discharge of waste material that are known to have a negative impact on the environment. Besides, Laboratory as well as plant is equipped with latest Machinery, Equipments, Technical personnel & Means of communications.

Due to supply of reliable quality, efficient follow up, scheduled delivery and prompt response to any matter, company wins good comments from customers.

We aimed at delivering real business value to our clients. For any interest, pls call on us or email us to get our best services.

Company Info

  • Company Name: Taizhou Volsen Chemical Co., Ltd.
  • Representative: Mr Chen
  • Product/Service: Efinaconazole Intermediates , Isavuconazole Intermediates , Obeticholic Acid Intermediates , Vilanterol Intermediates , Dolutegravir Intermediates , Umeclidinium Bromide
  • Capital (Million US $): 60000000RMB
  • Year Established: 2002
  • Total Annual Sales Volume (Million US $): Above US$100 Million
  • Export Percentage: 91% - 100%
  • Total Annual Purchase Volume (Million US $): Below US$1 Million
  • No. of Production Lines: 5
  • No. of R&D Staff: 91 -100 People
  • No. of QC Staff: 11 -20 People
  • OEM Services Provided: yes
  • Factory Size (Sq.meters): 30,000-50,000 square meters
  • Factory Location: Dongying Economic Development Zone , Dongying, Shandong,China
  • Contact Person: Ms. Amy Cheng
  • Tel: 86-576-88869393
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